10.6 Nails – Human Biology (2024)

Created by CK-12 Foundation/Adapted by Christine Miller

10.6Nails – Human Biology (1)

Painting nails with coloured polish for aesthetic reasons is nothing new. In fact, there is evidence of this practice dating back to at least 3000 BCE. Today, painting and otherwise decorating the nails is big business, with annual revenues in the billions of dollars in North America alone! With all the attention (and money) given to nails as decorative objects, it’s easy to forget that they also have important biological functions.

Nailsare accessory organs of the skin. They are made of sheets of dead keratinocytes and are found on the far (or distal) ends of the fingers and toes. The keratin in nails makes them hard, but flexible. Nails serve a number of purposes, including protecting the digits, enhancing sensations, and acting as tools.

10.6Nails – Human Biology (2)

A nail has three main parts: the root, plate, and free margin. Other structures around or under the nail include the nail bed, cuticle, and nail fold. These structures are shown in Figure 10.6.2.

  • Thenail rootis the portion of the nail found under the surface of the skin at the near (or proximal) end of the nail. It is where the nail begins.
  • Thenail plate(or body) is the portion of the nail that is external to the skin. It is the visible part of the nail.
  • Thefree marginis the portion of the nail that protrudes beyond the distal end of the finger or toe. This is the part that is cut or filed to keep the nail trimmed.
  • Thenail bed is the area of skin under the nail plate. It is pink incolour, due to the presence of capillaries in thedermis.
  • Thecuticleis a layer of dead epithelialcellsthat overlaps and covers the edge of the nail plate. It helps to seal the edges of the nail to prevent infection of the underlying tissues.
  • Thenail foldis a groove in the skin in which the side edges of the nail plate are embedded.

Nails grow from a deep layer of living epidermal tissue, known as thenail matrix, at the proximal end of the nail (see the bottom of the diagram in Figure 10.6.2). The nail matrix surrounds the nail root. It contains stem cells that divide to form keratinocytes, which are cells that produce keratin and make up the nail.

Formation of the Nail Root and Nail Plate

The keratinocytes produced by the nail matrix accumulate to form tough, hard, translucent sheets of deadcellsfilled with keratin. The sheets make up the nail root, which slowly grows out of the skin and becomes the nail plate when it reaches the skin surface. As the nail grows longer, the cells of the nail root and nail plate are pushed toward the distal end of the finger or toe by new cells being formed in the nail matrix. The upper epidermal cells of the nail bed also move along with the nail plate as it grows toward the tip of the digit.

The proximal end of the nail plate near the root has a whitish crescent shape called thelunula. This is where a small amount of the nail matrix is visible through the nail plate. The lunula is most pronounced in the nails of the thumbs, and may not be visible in the nails of the little fingers.

Rate of Nail Growth

Nails grow at an average rate of 3 mm a month. Fingernails, however, grow up to four times as fast as toenails. If a fingernail is lost, it takes between three and six months to regrow completely, whereas a toenail takes between 12 and 18 months to regrow. The actual rate of growth of an individual’s nails depends on many factors, including age, sex, season, diet, exercise level, and genes. If protected from breaking, nails can sometimes grow to be very long. The Chinese doctor in the photo below (Figure 10.6.3) has very long nails on two fingers of his left hand. This picture was taken in 1920 in China, where having long nails was a sign of aristocracy since it implied that one was wealthy enough to not have to do physical labour.

10.6Nails – Human Biology (3)

Both fingernails and toenails protect the soft tissues of the fingers and toes from injury. Fingernails also serve to enhance sensation and precise movements of the fingertips through the counter-pressure exerted on the pulp of the fingers by the nails. In addition, fingernails can function as several different types of tools. For example, they enable a fine precision grip like tweezers, and can also be used for cutting and scraping.

Healthcare providers, particularly EMTs, often examine the fingernail beds as a quick and easy indicator of oxygen saturation of the blood, or the amount of blood reaching the extremities. If the nail beds are bluish or purple, it is generally a sign of low oxygen saturation. To see if blood flow to the extremities is adequate, a blanch test may be done. In this test, a fingernail is briefly depressed to turn the nail bed white by forcing the blood out of its capillaries. When the pressure is released, the pink colour of the nail bed should return within a second or two if there is normal blood flow. If the return to a pink colour is delayed, then it can be an indicator of low blood volume, due to dehydration or shock.

10.6Nails – Human Biology (4)

How the visible portion of the nails appears can be used as an indicator of recent health status. In fact, nails have been used as diagnostic tools for hundreds — if not thousands — of years. Nail abnormalities, such as deep grooves, brittleness, discolouration, or unusually thin or thick nails, may indicate various illnesses, nutrient deficiencies, drug reactions, or other health problems.

Nails — especially toenails — are common sites of fungal infections (shown in Figure 10.6.4), causing nails to become thickened and yellowish in colour. Toenails are more often infected than fingernails because they are often confined in shoes, which creates a dark, warm, moist environment where fungi can thrive. Toes also tend to have less blood flow than fingers, making it harder for the immune system to detect and stop infections in toenails.

Although nails are harder and tougher than skin, they are also more permeable. Harmful substances may be absorbed through the nails and cause health problems. Some of the substances that can pass through the nails include the herbicide Paraquat, fungicidal agents such as miconazole (e.g., Monistat), and sodium hypochlorite, which is an ingredient in common household bleach. Care should be taken to protect the nails from such substances when handling or immersing the hands in them by wearing latex or rubber gloves.

10.6Nails – Human Biology (5)

Do you get regular manicures or pedicures from a nail technician? If so, there is a chance that you are putting your health at risk. Nail tools that are not properly disinfected between clients may transmit infections from one person to another. Cutting the cuticles with scissors may create breaks in the skin that let infective agents enter the body. Products such as acrylics, adhesives, and UV gels that are applied to the nails may be harmful, especially if they penetrate the nails and enter the skin.

Use the Internet to find several reliable sources that address the health risks of professional manicures or pedicures. Try to find answers to the following questions:

  1. What training and certification are required for professional nail technicians?
  2. What licenses and inspections are required for nail salons?
  3. What hygienic practices should be followed in nail salons to reduce the risk of infections being transmitted to clients?
  4. Which professional nail products are potentially harmful to thehuman bodyand which are safer?
  5. How likely is it to have an adverse health consequence when you get a professional manicure or pedicure?
  6. What steps can you take to ensure that a professional manicure or pedicure is safe?
  • Nailsare accessory organs of the skin, consisting of sheets of dead, keratin-filled keratinocytes. The keratin in nails makes them hard, but flexible.
  • A nail has three main parts: the nail root (which is under the epidermis), the nail plate (which is the visible part of the nail), and the free margin (which is the distal edge of the nail). Other structures under or around a nail include the nail bed, cuticle, and nail fold.
  • A nail grows from a deep layer of living epidermal tissues — called the nail matrix — at the proximal end of the nail. Stem cells in the nail matrix keep dividing to allow nail growth, forming first the nail root and then the nail plate as the nail continues to grow longer and emerges from theepidermis.
  • Fingernails grow faster than toenails. Actual rates of growth depend on many factors, such as age, sex, and season.
  • Functions of nails include protecting the digits, enhancing sensations and precise movements of the fingertips, and acting as tools.
  • The colour of the nail bed can be used to quickly assess oxygen and blood flow in a patient. How the nail plate grows out can reflect recent health problems, such as illness or nutrient deficiency.
  • Nails — and especially toenails — are prone to fungus infections. Nails are more permeable than skin and can absorb several harmful substances, such as herbicides.
  1. What are nails?
  2. Explain why most of the nail plate looks pink.
  3. Describe a lunula.
  4. Explain how a nail grows.
  5. Identify three functions of nails.
  6. Give several examples of how nails are related to health.
  7. What is the cuticle of the nail composed of?What is the function of the cuticle?Why is it a bad idea to cut the cuticle during a manicure?
  8. Is the nail plate composed of living or dead cells?

Longest Fingernails – Guinness World Records 60th Anniversary,
Guinness World Records, 2014.

5 Things Your Nails Can Say About Your Health, SciShow, 2015.

Claws vs. Nails – Matthew Borths, TED-Ed, 2019.

Attributions

Figure 10.6.1

Nails by allison-christine-vPrqHSLdF28[photo] by allison christine on Unsplash is used under the Unsplash License (https://unsplash.com/license).

Figure 10.6.2

Blausen_0406_FingerNailAnatomy by BruceBlaus on Wikimedia Commons is used under a CC BY 3.0 (https://creativecommons.org/licenses/by/3.0) license.

Figure 10.6.3

Chinese_doctor_with_long_finger_nails_(an_aristocrat),_ca.1920_(CHS-249) by Pierce, C.C. (Charles C.), 1861-1946 from the USC Digital Library on Wikimedia Commons is in the public domain (https://en.wikipedia.org/wiki/public_domain).

Figure 10.6.4

Toenail fungus Nagelpilz-3 by Pepsyrock on Wikimedia Commons is released into the public domain (https://en.wikipedia.org/wiki/public_domain).

Figure 10.6.5

OLYMPUS DIGITAL CAMERA by Stoive at the English language Wikipedia, on Wikimedia Commons is used under a CC BY-SA 3.0 (http://creativecommons.org/licenses/by-sa/3.0/) license.


References

Blausen.com staff. (2014). Medical gallery of Blausen Medical 2014. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436.

Guiness World Records. (2014, December 8). Longest fingernails – Guinness World Records 60th Anniversary. YouTube. https://www.youtube.com/watch?v=G35kPhbUZdg

SciShow. (2015, September 14). 5 things your nails can say about your health. YouTube. https://www.youtube.com/watch?v=aTSVHwzkYI4

TED-Ed. (2019, October 29). Claws vs. nails – Matthew Borths. YouTube. https://www.youtube.com/watch?v=7w2gCBL1MCg

definition

10.6 Nails – Human Biology (2024)

FAQs

How strong can human nails be? ›

HUMAN nails are as strong as a horse's hoof. And it is this structural strength that allows us to grip, scratch and even make those horrible nail-on-a-chalkboard screeches, without damaging our nails. Only primates evolved finger and toenails, probably to provide better grip on tree trunks and branches.

What are normal findings in nail assessment? ›

Normal findings might be documented as: “Nails are smooth, firm, clean with translucent colour, and no presence of clubbing. Capillary refill within 2 seconds.” Abnormal findings might be documented as: “Nail angle on thumbs is slightly greater than 180 degrees, capillary refill time is 5 seconds.”

What is a nail in biology? ›

Definition. The nail is an infolding of skin that occurs at the terminal end of each digit, creating four specialized components: proximal nail fold, matrix, nail bed, and hyponychium (Figure 108.1).

What is the maximum length of human nails? ›

How long? According to the Guinness World Records website, the current world record holder for longest fingernails is Christine “The Dutchess" Walton from Las Vegas, Nevada. The nails on her left hand measure a whopping 10 feet 2 inches, and the nails on her right hand measure 9 feet 7 inches.

Can a nail hold 10 pounds? ›

A 1 1/2-inch (4d) nail driven in at a 45-degree upward angle can hold as much as 20 pounds. That's enough for a small to medium picture frame or a small wall light or planter.

What is the weakest nail? ›

What Is the Weakest Nail Shape? Because of their straight-edge shapes, square- and coffin-shaped nails are more prone to breakage, Tuttle says.

What is a nail score? ›

The doctor will score the nail bed and the nail matrix, which is the area of specialized cells at the base of the nail that produces the nail plate. They assign each a score of 0–4, depending on the number of affected quadrants. This creates a total score of 0–8 for each nail.

What is normal nails? ›

Healthy fingernails are smooth, without pits or grooves. They're uniform in color and consistency and free of spots or discoloration. Sometimes fingernails develop harmless vertical ridges that run from the cuticle to the tip of the nail. Vertical ridges tend to become more prominent with age.

What can your nails tell you about your overall health? ›

Healthy nails are generally pink. Very pale nails may indicate illnesses, such as anemia, congestive heart failure or liver disease. Poor nutrition also may be a culprit. It's a good idea to get very pale nails checked by a doctor.

Are nails bones or skin? ›

Fingernails and toenails are made from skin cells. Structures that are made from skin cells are called skin appendages. Hairs are also skin appendages. The part that we call the nail is technically known as the “nail plate.” The nail plate is mostly made of a hard substance called keratin.

Are nails and hair dead cells? ›

The nails and hairs are made up of keratinized cells. These cells are found in the epidermis layer of the skin. The process due to which hair and nails grow is called keratinization. These are made up of dead cells which are not connected to the nerves of the brain.

How fast do nails grow? ›

Nails Grow Slowly

According to the NCBI, on average, fingernails grow around three millimeters per month. Three millimeters is about one-eight of an inch or about half the size of a pencil eraser. Toenails are even slower and grow at one-third of that rate at one millimeter per month.

How long are 10 nails? ›

For years, the building code defined a 10d common nail as 0.148 inches in diameter and 3 inches long, and that definition occurred in one location in the code.

Did Diana Armstrong cut her nails? ›

The American's daughter tragically died from an asthma attack in 1997, and Armstrong has decided to pay tribute to her in a fairly unusual way. Her 16-year-old daughter loved to do her nails, and as a result, Armstrong never trimmed them ever again.

Can nails grow back? ›

After a nail separates from the nail bed for whatever reason, it will not reattach. A new nail will have to grow back in its place. Nails grow back slowly. It takes about 6 months or longer for a fingernail and up to 18 months for a toenail to grow back.

Can fingernails be used as a weapon? ›

Nails are a dangerous literal weapon also to be wielding: sharp and fragile. It's so weird how some that I could easily crack and split could also take out an eyeball.

Can human nails be used for something? ›

For grooming

Just like primates in the jungle, human fingernails are useful for removing lice, ticks and other pests from our skin and hair.

What is the hardness of human finger nail? ›

The Common Objects for hardness comparisons are listed a column to the left as: Masonry Drill Bit, 8.5; Steel Nail, 6.5; Knife/Glass Plate, 5.5; Copper Penny, 3.5; and Fingernail, 2.5.

Are fingernails stronger than diamonds? ›

What is the hardest mineral in this group, calcite, quartz, diamond, or gold? - Quora. In moh's scale hardness; the calcite score is 3, the quartz score is 7, the diamond score is 10, and the pure gold score is 2.5. the hardness of the pure gold is the same as your fingernail.

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