Hypertrichosis (Werewolf Syndrome): Causes, Treatments, and Types (2024)

Hypertrichosis (werewolf syndrome) causes excessive hair growth anywhere on a person’s body. It can affect both sexes but is extremely rare.

The abnormal hair growth may cover the face and body or in small patches. Hypertrichosis can appear at birth or develop over time.

Read on to learn about the various types of hypertrichosis, what may cause it, and how it’s treated.

There are several types of hypertrichosis:

  • Congenital hypertrichosis lanuginosa: It first appears as normal lanugo, the fine hair found on a baby, at birth. But instead of disappearing during subsequent weeks, the soft fine hair continues to grow in various places on the baby’s body.
  • Congenital hypertrichosis terminalis: Abnormal hair growth begins at birth and continues throughout a person’s life. Hair, usually long and thick, covers the person’s face and body.
  • Nevoid hypertrichosis: Excessive hair growth of any kind appears in a defined area. In few cases, more than one patch of hair is present.
  • Hirsutism: This form of hypertrichosis is limited to women. It results in dark, thick hair growing in places women normally don’t have hair, such as their face, chest, and back.
  • Acquired hypertrichosis: Unlike congenital hypertrichosis, the acquired form of the disease tends to develop later in life. As well, it results in two types of hair other than lanugo: vellus hair or terminal hair. Excess hair may grow in small patches or on all hair-growing areas of a person’s body.

As mentioned previously, hypertrichosis can occur at birth or develop later in life.

Hypertrichosis usually produces one of three types of hair:

  • Vellus: The follicles for these hairs are usually short (less than 1/13th of an inch long, according to the Indian Journal of Endocrinology and Metabolism). They may be located anywhere but the soles of your feet, backs of your ears, lips, and palms, or on scar tissue. Vellus may be pigmented or nonpigmented.
  • Lanugo: This type of hair is very soft and fine, like that on the body of a newborn baby. It usually has no pigment. Most babies lose lanugo within a few days or weeks after birth. If hypertrichosis is present, lanugo may remain unless treated and removed.
  • Terminal: The hair is long and thick, and usually very dark.

Women with hirsutism develop stiff, dark body hair in places such as their face, chest, and back.

Another common symptom of hypertrichosis is a problem with your gums or teeth. Some teeth may be missing, or your gums may be enlarged.

The causes of hypertrichosis aren’t well understood, though there is a form of the disease that tends to run in families.

Congenital hypertrichosis may be caused by reactivation of genes that cause hair growth. The genes that caused extensive hair growth in early man have “shut down” during the course of evolution. By a mistake that still has no known cause, these hair-growth genes “turn on” while a baby is still in the womb.

Acquired hypertrichosis may have several origins. When hair growth is everywhere or in random patches, possible causes include:

  • porphyria cutanea tarda, a condition in which your skin is especially sensitive to light
  • malnutrition
  • diet or an eating disorder like anorexia nervosa
  • cancer
  • certain drugs, such as androgenic steroids, the hair-growth drug minoxidil, and cyclosporine (Sandimmune)

Hypertrichosis occurring in specific places on your body can develop from:

  • lichen simplex, a chronic skin condition that leads to itchiness and repeated scratching of a patch of skin
  • temporary use of a plaster cast
  • increased vascularity, a bodybuilding strategy to develop prominent blood vessels near the surface of the skin

Hypertrichosis, regardless of type, is infrequent. Congenital hypertrichosis lanuginosa, for example, is extremely rare. Only about 50 cases of this kind of hypertrichosis have ever been documented, according to JAMA Dermatology. Hirsutism is much more common, affecting about 7 percent of the female population in the U.S.

Hypertrichosis has no cure, and you can’t do anything to prevent the congenital form of the disease. The risk of certain forms of acquired hypertrichosis may be lowered by avoiding certain medications, such as minoxidil.

Treating hypertrichosis involves the removal of hair through a variety of short-term methods. They include:

  • shaving
  • chemical epilation
  • waxing
  • plucking
  • hair bleaching

All of these methods are temporary solutions. They also run the risk of causing painful or uncomfortable skin irritation. And on some parts of your body, these treatments aren’t easily done.

Long-term treatments include electrolysis and laser surgery. Electrolysis is the destruction of individual hair follicles with small electrical charges. Laser surgery involves the application of a special laser light over several hairs at one time. Hair loss can often be permanent with these treatments, though you may need a few sessions to complete the job.

Read more: Excessive or unwanted hair in women »

Hypertrichosis (Werewolf Syndrome): Causes, Treatments, and Types (2024)

FAQs

Hypertrichosis (Werewolf Syndrome): Causes, Treatments, and Types? ›

Hypertrichosis has no cure, and you can't do anything to prevent the congenital form of the disease. The risk of certain forms of acquired hypertrichosis may be lowered by avoiding certain medications, such as minoxidil. Treating hypertrichosis involves the removal of hair through a variety of short-term methods.

What are the treatments for hypertrichosis? ›

Some common over-the-counter methods for managing this condition include:
  • Shaving.
  • Plucking.
  • Waxing.
  • Depilatories.
  • Hair bleaching.

How do you treat werewolf syndrome? ›

Hypertrichosis has no cure, and you can't do anything to prevent the congenital form of the disease. The risk of certain forms of acquired hypertrichosis may be lowered by avoiding certain medications, such as minoxidil. Treating hypertrichosis involves the removal of hair through a variety of short-term methods.

What drugs cause hypertrichosis? ›

Drugs most often cause acquired generalized hypertrichosis.
  • Antibiotics such as streptomycin.
  • Anti-inflammatory drugs such as benoxaprofen and corticosteroids.
  • Vasodilators (diazoxide, minoxidil, prostaglandin E1)
  • Diuretics (acetazolamide)
  • Anticonvulsants (phenytoin)

Is hypertrichosis life threatening? ›

Congenital hypertrichosis lanuginosa is not associated with an increased mortality rate. No documented long-term medical or physical morbidities are associated with congenital hypertrichosis lanuginosa.

How do you treat Hypotrichosis? ›

Most forms of hypotrichosis have no treatment. An exception involving hypotrichosis of the eyelashes exist, a medication called Latisse, the brand name for bimatoprost.

Is werewolf syndrome rare? ›

Hypertrichosis, also known as werewolf syndrome, is a rare condition characterized by excessive hair growth that may develop all over the body or be isolated to specific areas.

What triggers a werewolf? ›

Most werewolves have a trigger that makes them transform. For example: If a werewolves is in human form and it gets to hyper, it will transform. Other triggers are: getting to angry, getting hurt, getting too much adrenaline, or to protect something or someone.

Is lycanthropy treatable? ›

Clinical lycanthropy is treated on a case-by-case basis. Doctors might give you antidepressants or mood-regulating medications if you also have depression or mania. They might give you antipsychotic medications. Symptoms usually get better or go away over time.

How do you reverse hypertrichosis? ›

Addressing the underlying cause or changing medications is usually enough to resolve the hair growth. For people who are born with hypertrichosis, especially severe forms, there isn't typically a one-time treatment, though hair removal methods like waxing and electrolysis can help.

Who is the girl with werewolf syndrome? ›

Also known as “werewolf syndrome,” hypertrichosis is extremely rare, with fewer than 100 recorded cases since the Middle Ages. Little Adik was also born without nostrils. However, the hirsute child's affliction didn't prevent her from hobnobbing with the Southeast Asian nation's rulers.

Why am I suddenly growing chin hair? ›

“Chin hair is more common in women with higher levels of androgens (including testosterone), certain medical conditions such as polycystic ovary syndrome (PCOS), and women with a family history of excessive hair growth (hirsutism),” says Azza Halim, MD, a physician at Azza MD Beauty.

Can werewolf syndrome be cured? ›

There is no cure for any congenital forms of hypertrichosis.

What is a interesting fact about werewolf syndrome? ›

Werewolf syndrome is medically known as hypertrichosis. It is a disorder that is characterized by excessive body hair. Typically the entire body with the exception of the palms of the hands and the soles of the feet are covered in dense hair, which can resemble fur.

What hormone imbalance causes hypertrichosis? ›

Hypertrichosis is the presence of abundant body hair that is not caused by androgen. It can be hereditary or acquired. Cushing's disease, acromegaly, and hypothyroidism are the main endocrine causes of acquired hypertrichosis [33].

Can hypertrichosis be treated with laser? ›

Possible causes include the effect of inflammatory mediators and subtherapeutic thermal injury causing induction of the hair cycle. Treatment for paradoxical hypertrichosis is laser therapy of the affected area.

Do people with hypertrichosis shave? ›

The currently available treatment methods include cosmetic procedures (bleaching, trimming, shaving, plucking, waxing, chemical depilatories, and electrosurgical epilation), and hair removal using light sources and lasers.

Does electrolysis work on hypertrichosis? ›

Electrolysis satisfactorily removes hair from women and men with hypertrichosis, but women with hirsutism require concomitant hormonal management.

What causes hypertrichosis in the face? ›

Causes include:
  • malnutrition.
  • poor diet or certain eating disorders, such as anorexia nervosa.
  • certain drugs and medications, such as hair growth drugs, certain immunosuppressants, and androgenic steroids.
  • cancer and cell mutation.
  • autoimmune and infectious diseases affecting the skin.
Nov 16, 2017

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